Domains of high Ca 2 beneath the plasma
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چکیده
local Ca2 changes and effects on cell function has been Robert Marsault, Marta Murgia, very difficult to obtain. In fact, while the Ca2 dependence Tullio Pozzan and Rosario Rizzuto1 of various processes occurring at the cell surface has been Department of Biomedical Sciences and CNR, Center for the Study of investigated thoroughly in a large number of cell models, Biomembranes, University of Padova, Via Trieste 75, 35121 Padova, the measurement of Ca2 concentration in this restricted Italy cytosolic space is a still unsolved experimental task. 1Corresponding author We have recently described the targeting of the Ca2 e-mail: [email protected] sensitive photoprotein aequorin to the lumen of various
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